Send the page " " to a friend, relative, colleague or yourself. We do not record any personal information entered above. Oral non-sedating antihistamine and sympathomimetic decongestant combination Used for temporary relief of sneezing, rhinorrhea, nasal congestion and itchy, watery eyes and itchy throat throat due to the common cold or due to hay fever or other upper respiratory allergies.
Less than 12 years: Safety and efficacy have not been established. Avoid use; combination product is not recommended due to fixed dosage and inability to reduce initial dosage appropriately for hepatic disease.
Use of the extended-release hour tablets is not recommended, as the fixed dosage does not allow for proper dose reduction. Intermittent hemodialysis See dosage for patients with renal impairment. Loratadine is not removed by hemodialysis. Hemodialysis minimally removes pseudoephedrine from the blood.
Extended-release tablets: Loratadine; pseudoephedrine is administered orally with a glass of water and may be administered without regard to meals. Do not cut, crush or chew the extended-release tablets. Pseudoephedrine-containing products are contraindicated in individuals receiving MAOI therapy or within 2 weeks of such therapy see Drug Interactions. Because the doses of this fixed combination product cannot be individually titrated and hepatic insufficiency results in a reduced clearance of loratadine relative to pseudoephedrine, Claritin-D 12 hour and 24 hour extended-release tablets should be avoided in patients with hepatic disease.
Loratadine is extensively metabolized in the liver by the cytochrome P system. Metabolism most likely occurs through the 3A4 isozyme, since interaction studies involving concurrent use of loratadine and potent 3A4 inhibitors such as ketoconazole and erythromycin have shown a several-fold increase in serum loratadine concentrations.
Unlike astemizole and terfenadine, loratadine has not yet been associated with torsades de pointes. Loratadine; pseudoephedrine may cause drowsiness in individual patients; therefore patients receiving this combination should be advised to avoid driving or operating machinery until the effects of the product are known.
Use sympathomimetic agents with caution in patients with renal disease. Patients who have a history of dysphagia i.
Claritin-D® Tablets 24-Hour
Rare cases of mechanical obstruction have been reported in patients taking Claritin-D 24 hour tablets loratadine; pseudoephedrine. In some cases, endoscopy was required to remove the tablet. Most, but not all, of these patients had a history of difficulty swallowing, or had upper GI narrowing or abnormal esophageal peristalsis. In Decemberan oval-shaped tablet replaced the round-shaped tablet of Claritin-D 24 hour. It is not known whether the new formulation of Claritin-D 24 hour tablets has the potential to cause mechanical obstruction.
Patients should be reminded to drink a full glass of water when taking Claritin-D 24 hour tablets. Claritin-D 12 hour tablets have not been associated with upper GI tract obstruction. Due to its pseudoephedrine component, this product should be used with caution in patients with diabetes mellitus or hyperthyroidism since it can exacerbate these conditions.
It is contraindicated for use in patients with closed-angle glaucoma or urinary retention due to prostatic hypertrophy. Well-controlled hypertensive patients receiving pseudoephedrine at recommended doses 60 mg PO four times daily do not appear at risk for elevations in blood pressure. Since pseudoephedrine is a vasoconstrictor and may increase heart rate and blood pressure via sympathomimetic effects, it should be avoided in patients with uncontrolled or severe hypertension or significant coronary artery disease including acute myocardial infarction, angina, or history of myocardial infarction.
Considerable caution should be used in patients with controlled or mild hypertension, heart failure, cardiomyopathy, acute cardiac arrhythmias tachycardiaor other cardiac disease. The safety and effectiveness of loratadine; pseudoephedrine combination products have not been established in infants and children less than 12 years of age. The adverse effects of sympathomimetics, such as pseudoephedrine, can be severe, especially in infants and toddlers; CNS stimulation, hypertension and tachycardia may occur.
Antihistamines are not administered to neonates due to CNS stimulation and potential seizure risks. In Januarythe CDC warned caregivers and healthcare providers of the risk for serious injury or fatal overdose from the administration of cough and cold products to children and infants less than 2 years of age; some cases occurred due to inadvertent inappropriate administration.
The report estimated that 1, children less than 2 years of age were treated in emergency departments during to for adverse events related to cough and cold medications. In Octoberthe FDA Nonprescription Drug Advisory Committee and the Pediatric Advisory Committee recommended that nonprescription cough and cold products containing pseudoephedrine, dextromethorphan, chlorpheniramine, diphenhydramine, brompheniramine, phenylephrine, clemastine, or guaifenesin not be used in children less than 6 years of age.
The FDA recommends that if cough and cold products are used in children, labels should be read carefully, caution should be used when administering multiple products, and only measuring devices specifically designed for use with medications should be used. Clinicians should thoroughly assess each patient's use of similar products, both prescription and nonprescription, to avoid duplication of therapy and the potential for inadvertent overdose.
Because loratadine; pseudoephedrine is available for non-prescription use, pregnancy risk for the use of the combination is unknown.Medically reviewed by Carmen Fookes, BPharm. Last updated on Mar 23, If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:.
Notes: In general, seniors or children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, seizures or people who take other medications are more at risk of developing a wider range of side effects. For a complete list of all side effects, click here. Bottom Line Pseudoephedrine effectively relieves nasal and sinus congestion and is found in several behind-the-counter combination cold and flu remedies.
Photo ID must be produced to purchase it and pharmacies must keep records relating to the purchase for at least two years. Sleeplessness is a common side effect.
Medicines that interact with pseudoephedrine may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with pseudoephedrine. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Note that this list is not all-inclusive and includes only common medications that may interact with pseudoephedrine.
You should refer to the prescribing information for pseudoephedrine for a complete list of interactions. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use pseudoephedrine only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Skip to Content. Patient Tips pseudoephedrine Print Share.
How it works Pseudoephedrine is a decongestant that constricts shrinks dilated blood vessels within the nose, relieving congestion. It causes vasoconstriction by stimulating primarily alpha-adrenergic receptors. It also has weak activity at beta-adrenergic receptors.
It is chemically related to ephedrine, but with less central nervous system activity fewer effects on the brain. Pseudoephedrine belongs to the class of medicines known as nasal decongestants.
It may also be called a sympathomimetic. Upsides Significantly more effective as a decongestant than phenylephrine. Tablets, chewable tablets, liquid and nasal preparations of pseudoephedrine effectively treat nasal and sinus congestion; however, the sale of cold and flu products containing pseudoephedrine is limited to behind the counter because pseudoephedrine may be used for the illicit production of methamphetamine.
Generic pseudoephedrine is available.This is a subreddit for Clandestine Chemistry. We do not condone breaking any laws in your area, but are more than happy for you to share your dreams with us.
Claritin-D® Tablets 12-Hour
BatchPurifier - file metadata cleaner for windows. New method of pseudoephedrine extraction self. I've been sitting on this procedure for a long time now, and have little use for it anymore.
The only solvent needed is water. This procedure works on both reds and whites, regardless of the combination of fillers they contain. Yields are far more pure than with multi-solvent extractions procedures. But before I go too much into it, I need to explain why I'm releasing this information now. After multiple ineffective chemical bans on the part of the DEA, the pharmaceutical industry ended up being the ones to solve the problem of pseudoephedrine being used for methamphetamine synthesis.
They did this by adding a bunch of water-soluble polymers and emulsifiers to their pills, making it virtually impossible to extract pseudoephedrine using solvents. Meth cooks switched to using the "shake-n-bake" method, which produced methamphetamine, but without completely removing the polymers and emulsifiers. Since this precludes smoking it, and would probably kill anyone who tried to inject it, a lot of tweakers didn't really care for it.
Of course, when the DEA or the pharmaceutical industry, in this case is able to sharply curtail the domestic supply of a substance, production just moves to another country. In this case, it moved to Mexico. Between andMexican narcos took over production of the entire US supply of methamphetamine. Inthey started shipping heavily-cut racemic methamphetamine, containing n-isopropylbenzylamine or possible a different n-alkylbenzylamine hydrochloride salt as the main filler, often with a pyrrolidine-based cathinone probably aPVP, aka flakka as a minor component.
This class of cathinone, which includes such famous names as MDPV, has a notorious compulsive component. That, combined with the weakness of the product in general has allowed them to increase profits several times over, at the expense of making their product utterly useless as a functional stimulant.
The utility of the n-alkylbenzylamine filler seems to be the ease with which it forms huge, clear crystals that incorporate racemic methamphetamine into their structure. Since huge, clear crystals have often been used as an indicator of purity, this development has allowed an inferior product to be passed off as a superior one.This is a subreddit for Clandestine Chemistry.
We do not condone breaking any laws in your area, but are more than happy for you to share your dreams with us. BatchPurifier - file metadata cleaner for windows. Did the loratadine aka antihistamine will fukes up the batch like when you have paracetamol in your product.
Is there any method for synthesizing almost pure pseudoephedrine from Claritin D which contains pseudoephedrine and loratadine? I will be very grateful if any answer appears!Law of conservation of mass formula
You have a LOT to learn. Start with how to get your pseudo ephedrine. The process is called extraction. Try a google search for "ectraction of pseudoephedrine from pills" or something like that. Don't give up, the knowledge is out there. No one is going to just spoon feed you, you need to prove you can do the legwork, or that you have at least tried to find your own answers How can you separate multiple solids from a dry mixture?
If you can separate them, which one is your product and how do you know? Here's a hint on extraction: An impure solid is dissolved in a liquid Another solid and another liquid are added and allowed to react.
The second liquid has to be insoluble in the first, when combined they will form 2 separate layers. Once the reaction is completed, nearly pure compoud of interest will be in one of the liquid layers called phases. All that need be done is separate the 2 phases and evaporate away the solvent, leaving the desired product behind. That has alone has helped me a ton.
I don't need to know what chems, just what is going on and why. Thank you. Generally though you extract the active components of the pills by crushing them, mixing in water, alcohol, or some other solvent, and filtering the solution hopefully with vac filtration hint: an aspirator attached to a standard sink produces sufficient suction through a thick-walled vacuum hose.
Dissolve them both in near-boiling methanol, then let it cool way down. Substance 1 will precipitate and form crystals while Substance 2 stay in solution.
The Combat Methamphetamine Epidemic Act of was signed into law to regulate retail over-the-counter sales of pseudoephedrine. By law, all products containing psuedoephedrine must now be sold behind the pharmacy counter. However, in most states, products containing psuedoephedrine remain available without a prescription.
Active ingredient in each tablet : Loratadine 5 mg Antihistamine X Antihistamine Medication that relieves symptoms of sneezing, itching and runny nose by blocking histamine receptors.
Pseudoephedrine sulphate mg Nasal decongestant X Nasal decongestant Medication that shrinks swollen nasal tissues to relieve symptoms of nasal swelling, congestion, and mucus secretion.Chromosome worksheet doc
Inactive Ingredients: Croscarmellose sodium, dibasic calcium phosphate, hypromellose, lactose monohydrate, magnesium stearate, pharmaceutical ink, povidone, titanium dioxide. When using this product do not take more than directed.
Taking more than directed may cause drowsiness. Keep out of reach of children.Good night and god bless quote
In case of overdose, get medical help or contact a Poison Control Center right away. Safety sealed. Applicable laws and regulations specify identification requirements and quantity limits. The Combat Methamphetamine Epidemic Act of was signed into law to regulate retail over-the-counter sales of pseudoephedrine because of its use in the manufacture of illegal drugs. However, in most states, products containing pseudoephedrine remain available without a prescription.
Feel better faster with the leading adult multi-symptom allergy product. The information on this site is intended for healthcare professionals in the United States and is not intended for the general public. I am a Healthcare Professional. I am not a Healthcare Professional. Get A Coupon. You will need to provide your identification before purchase. Adults and children 12 years and over 1 tablet every 12 hours; not more than 2 tablet in 24 hours Children under 12 years of age Ask a doctor Consumers with liver or kidney disease Ask a doctor.Ask for it at the pharmacy counter.
Learn More. This is a non-prescription item stored behind the pharmacy counter. It is not available for sale online.
Here's what you need to know about buying it:. The Combat Methamphetamine Epidemic Act of was signed into law to regulate retail over-the-counter sales of pseudoephedrine. By law, all products containing pseudoephedrine must now be sold behind the pharmacy counter.
However, in most states, products containing pseudoephedrine remain available without a prescription. Active ingredient in each tablet : Loratadine 10 mg Antihistamine X Antihistamine Medication that relieves symptoms of sneezing, itching and runny nose by blocking histamine receptors. Pseudoephedrine sulfate mg Nasal Decongestant X Nasal Decongestant Medication that shrinks swollen nasal tissues to relieve symptoms of nasal swelling, congestion, and mucus secretion.
Inactive Ingredients: Carnauba wax, dibasic calcium phosphate dihydrate, ethylcellulose, hydroxypropyl cellulose, hypromellose, magnesium stearate, pharmaceutical ink, polyethylene glycol, povidone, silicon dioxide, sucrose, titanium dioxidez. When using this product do not take more than directe d. Taking more than directed may cause drowsiness. Keep out of reach of children.
In case of overdose, get medical help or contact a Poison Control Center right away. Safety sealed.
Applicable laws and regulations specify identification requirements and quantity limits. The Combat Methamphetamine Epidemic Act of was signed into law to regulate retail over-the-counter sales of pseudoephedrine because of its use in the manufacture of illegal drugs. This powerful tablet relieves common allergy symptoms such as sneezing, runny nose, itchy, watery eyes and itchy nose or throat, plus sinus congestion Feel better faster with the leading adult multi-symptom allergy product.
The information on this site is intended for healthcare professionals in the United States and is not intended for the general public. I am a Healthcare Professional. I am not a Healthcare Professional. Get A Coupon.Pet ki bimari ke lakshan
You will need to provide your identification before purchase. Adults and children 12 years and over 1 tablet daily with a full glass of water; not more than 1 tablet in 24 hours Children under 12 years of age Ask a doctor Consumers with liver or kidney disease Ask a doctor. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if you have: Heart disease Thyroid disease High blood pressure Diabetes Trouble urinating due to an enlarged prostate gland Liver or kidney disease. Your doctor should determine if you need a different dose. Stop use and ask a doctor if: An allergic reaction to this product occurs. Seek medical help right away Symptoms do not improve within 7 days or are accompanied by a fever Nervousness, dizziness or sleeplessness occurs If pregnant or breast-feedingask a health professional before use.
Allergies Or Cold.We were very satisfied with our tour (8 days around Iceland). The group was a good size (16). Our tour guide, Alfred, was great and very knowledgeable. All of the restaurants and hotels were acceptable. We got to see all of the major highlights and a few hidden things we wouldn't have found on our own. It was nice to have someone else drive and take care of logistics. We have just returned from a week's self touring holiday of Reykjavik and Southern Iceland, arranged through Nordic Visitor.
From the moment I first contacted the company I knew I had chosen wisely. Their agent, Helga, was efficient, courteous, prompt with responses and very patient as we tweaked our trip. Her suggestions gave us a custom-made itinerary which took us to the best that Southern Iceland had to offer.
After 2 nights in Reykjavik, we stayed at different hotels every night and they were all great. Granted a few didn't look much from the outside, but inside they were brilliant and we had the best rooms they had to offer. Our mid-way stop was at the Fosshotel Vatnajokull, near Hofn, and the view from the window was of three glaciers - awesome.
If you are thinking of a holiday in Iceland then use Nordic Visitor and always ask for Helga - she was brilliant. We've recently returned from holiday in Iceland. I booked us on the Iceland Full Circle self guided tour through Nordic Visitor. Hilmar was absolutely fantastic to deal with. He was very patient with me as I tried to work through dates and added excursions and always provided quick, informative responses.
The package we received upon arrival was well put together and allowed us to navigate around the country with confidence. Everything had been considered and taken care of. The accommodations were fantastic. We had a self-created situation when we arrived at the airport. Hilmar rang the hotel later in the day to make certain we were settled in with no more issues.
He also called in advance when a glacier tour was cancelled due to a storm. Iceland can be a little intimidating. Nordic Visitor's preparations and assistance made it even more wonderful than we hoped and imagined it could be. I not only highly recommend this company, I have already referred friends to them and will be using them again when we return to Iceland in the hopefully not too distant future. We have just returned from a 9 day bus trip arranged by Nordic Visitor.
As we arrived, there was a potential strike in the offing. We called at the office and they could not have done more for us in helping to rearrange our trip.
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